|Full Name||chymotrypsin-like elastase family, member 3B|
|Product Description||Rabbit polyclonal antibody to ELA3B (elastase 3B, pancreatic)|
|Background||Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. [provided by RefSeq]|
|Synonyms||CBPP antibody, E1 antibody, EL-1 antibody, ELA3B antibody, CELA3B antibody, cholesterol-binding pancreatic protease antibody, fecal elastase 1 antibody, proteinase E antibody, protease E antibody, "elastase 3B, pancreatic antibody", elastase 1 antibody, elastase IIIB antibody, chymotrypsin-like elastase family member 3B antibody, pancreatic endopeptidase E antibody, pancreatic elastase 1 antibody, elastase-3B antibody, "chymotrypsin-like elastase family, member 3B antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ELA3B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rat (82%), Rhesus Monkey (94%), Bovine (87%)|