|Full Name||epoxide hydrolase 1, microsomal (xenobiotic)|
|Product Description||Rabbit Polyclonal antibody to EPHX1 (epoxide hydrolase 1, microsomal (xenobiotic))|
|Background||Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.|
|Synonyms||EPHX antibody, EPOX antibody, MEH antibody, EPHX1 antibody, epoxide hydrolase 1 antibody, epoxide hydratase antibody, "epoxide hydrolase 1, microsomal (xenobiotic) antibody"|
|Cellular Localization||Microsome membrane; Single-pass membrane protein , Endoplasmic reticulum membrane; Single-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EPHX1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (86%), Pig (88%), Rabbit (81%), Rhesus Monkey (96%), Bovine (88%)|