ERK2 antibody [N2C3]
|Applications||IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||41 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain , *SD Rat brain thalamus , *SD Rat brain amygdala|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||mitogen-activated protein kinase 1|
|Product Description||Rabbit Polyclonal antibody to ERK2 (mitogen-activated protein kinase 1)|
|Background||The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq]|
|Synonyms||ERK antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, MAPK1 antibody, MAP kinase 2 antibody, extracellular signal-regulated kinase 2 antibody, p42-MAPK antibody, protein tyrosine kinase ERK2 antibody, MAP kinase 1 antibody, mitogen-activated protein kinase 1 antibody, MAP kinase isoform p42 antibody, MAPK 2 antibody, ERK-2 antibody, mitogen-activated protein kinase 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ERK2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Pig, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Dog, Chicken, Bovine|
|Predict Reactivity Note||Zebrafish (95%), Xenopus laevis (97%), Dog (100%), Chicken (99%), Bovine (99%)|