|Full Name||mitogen-activated protein kinase 7|
|Product Description||Rabbit polyclonal antibody to ERK5 (mitogen-activated protein kinase 7)|
|Background||The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq]|
|Synonyms||BMK1 antibody, ERK4 antibody, ERK5 antibody, PRKM7 antibody, MAPK7 antibody, extracellular-signal-regulated kinase 5 antibody, MAPK 7 antibody, BMK1 kinase antibody, ERK-5 antibody, BMK-1 antibody, MAP kinase 7 antibody, extracellular signal-regulated kinase 5 antibody, mitogen-activated protein kinase 7 antibody, big MAP kinase 1 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human ERK5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (100%), Rat (100%), Bovine (98%)|