|Applications||ICC/IF, IHC-P, IP, WB, ChIP assay|
Not tested in other applications.
| ChIP assay||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||53 kDa (note)
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)|
|Product Description||Rabbit Polyclonal antibody to ETS2 (v-ets erythroblastosis virus E26 oncogene homolog 2 (avian))|
|Background||ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]|
|Synonyms||ETS2IT1 antibody, ETS2 antibody, oncogene ETS-2 antibody, v-ets avian erythroblastosis virus E2 oncogene homolog 2 antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 2 antibody, protein C-ets-2 antibody, v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ETS2. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (87%), Bovine (90%)|