|Full Name||transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)|
|Product Description||Rabbit Polyclonal antibody to Elongin A (transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A))|
|Background||This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq]|
|Synonyms||EloA antibody, FLJ38760 antibody, FLJ42849 antibody, SIII antibody, SIII p110 antibody, TCEB3A antibody, TCEB3 antibody, transcription elongation factor B alpha subunit antibody, elongin-A antibody, transcription elongation factor B polypeptide 3 antibody, elongin 110 kDa subunit antibody, RNA polymerase II transcription factor SIII subunit A1 antibody, "transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Elongin A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (89%), Rat (89%)|