EphB3 antibody [C1C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||110 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||EPH receptor B3|
|Product Description||Rabbit Polyclonal antibody to EphB3|
|Background||Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq]|
|Synonyms||ETK2 antibody, HEK2 antibody, TYRO6 antibody, EPHB3 antibody, ephrin type-B receptor 3 antibody, EPH-like tyrosine kinase-2 antibody, embryonic kinase 2 antibody, EPH-like kinase 2 antibody, EPH-like tyrosine kinase 2 antibody, tyrosine-protein kinase TYRO6 antibody, human embryo kinase 2 antibody, EK2 antibody, EPH receptor B3 antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EPH receptor B3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (99%), Xenopus laevis (88%), Bovine (100%)|