|Full Name||EPH receptor B4|
|Product Description||Rabbit Polyclonal antibody to EphB4|
|Background||Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq]|
|Synonyms||HTK antibody, MYK1 antibody, TYRO11 antibody, EPHB4 antibody, soluble EPHB4 variant 2 antibody, tyrosine-protein kinase TYRO11 antibody, hepatoma transmembrane kinase antibody, soluble EPHB4 variant 1 antibody, soluble EPHB4 variant 3 antibody, ephrin receptor EphB4 antibody, ephrin type-B receptor 4 antibody, tyrosine-protein kinase receptor HTK antibody, EPH receptor B4 antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Eph receptor B4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (91%), Bovine (96%)|