|Full Name||EPH receptor B6|
|Product Description||Rabbit Polyclonal antibody to EphB6|
|Background||Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands. [provided by RefSeq]|
|Synonyms||HEP antibody, MGC129910 antibody, MGC129911 antibody, EPHB6 antibody, ephrin type-B receptor 6 antibody, tyrosine-protein kinase-defective receptor EPH-6 antibody, EPH receptor B6 antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein , Isoform 3: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Eph Receptor B6. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey|
|Predict Reactivity Note||Mouse (93%), Rat (93%), Rhesus Monkey (98%)|