|Full Name||epidermal growth factor receptor pathway substrate 15|
|Product Description||Rabbit Polyclonal antibody to Eps15 (epidermal growth factor receptor substrate 15)|
|Background||This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]|
|Synonyms||AF-1P antibody, AF1P antibody, MLLT5 antibody, EPS15 antibody, ALL1 fused gene from chromosome 1 antibody, epidermal growth factor receptor substrate 15 antibody, protein AF-1p antibody, epidermal growth factor receptor pathway substrate 15 antibody|
|Cellular Localization||Cytoplasm , Cell membrane; Peripheral membrane protein; Cytoplasmic side , Isoform 2: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Eps15. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (100%), Bovine (100%)|