Estrogen Receptor beta antibody [N2C2], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||59 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , GC1 , GC1 co-transfected ER-beta (NM_207707) , NIH-3T3 , *U2OS , *HEC-1A|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||estrogen receptor 2 (ER beta)|
|Product Description||Rabbit Polyclonal antibody to Estrogen Receptor beta (estrogen receptor 2 (ER beta))|
|Background||This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq]|
|Synonyms||ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ESR2 antibody, estrogen nuclear receptor beta variant a antibody, estrogen nuclear receptor beta variant b antibody, estrogen receptor beta antibody, estrogen receptor beta 4 antibody, nuclear receptor subfamily 3 group A member 2 antibody, estrogen receptor 2 (ER beta) antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Estrogen Receptor beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (88%), Chicken (84%), Sheep (91%), Rhesus Monkey (98%), Bovine (91%)|