|Product Description||Rabbit Polyclonal antibody to Ezrin (ezrin)|
|Background||The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq]|
|Synonyms||CVIL antibody, CVL antibody, DKFZp762H157 antibody, FLJ26216 antibody, MGC1584 antibody, VIL2 antibody, EZR antibody, villin-2 antibody, ezrin antibody, cytovillin 2 antibody, villin 2 (ezrin) antibody, p81 antibody|
|Cellular Localization||Apical cell membrane; Peripheral membrane protein; Cytoplasmic side , Cell projection , microvillus membrane; Peripheral membrane protein; Cytoplasmic side , ruffle membrane; Peripheral membrane protein; Cytoplasmic side , Cytoplasm , cell cortex , cytosk|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Ezrin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Dog, Rabbit, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Xenopus laevis (85%), Dog (98%), Rabbit (94%), Chicken (92%), Chimpanzee (99%), Bovine (96%)|