FACL4 antibody [C3], C-term
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||79 kDa (note)
|Positive Controls||HeLa , NT2D1 , NIH-3T3 , JC , BCL-1|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||acyl-CoA synthetase long-chain family member 4|
|Product Description||Rabbit Polyclonal antibody to FACL4 (acyl-CoA synthetase long-chain family member 4)|
|Background||The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]|
|Synonyms||ACS4 antibody, FACL4 antibody, LACS4 antibody, MRX63 antibody, MRX68 antibody, ACSL4 antibody, acyl-CoA synthetase 4 antibody, long-chain acyl-CoA synthetase 4 antibody, lignoceroyl-CoA synthase antibody, LACS 4 antibody, long-chain fatty-acid-Coenzyme A ligase 4 antibody, "fatty-acid-Coenzyme A ligase, long-chain 4 antibody", long-chain-fatty-acid--CoA ligase 4 antibody, acyl-CoA synthetase long-chain family member 4 antibody|
|Cellular Localization||Mitochondrion outer membrane; Single-pass type III membrane protein , Peroxisome membrane; Single-pass type III membrane protein , Microsome membrane; Single-pass type III membrane protein , Endoplasmic reticulum membrane; Single-pass type III membrane pr|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FACL4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rhesus Monkey|
|Predict Reactivity Note||Pig (100%), Rhesus Monkey (100%)|