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1 .GTX110546-pro FADD Protein

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FADD Protein


  • ApplicationsWB
Cat No: GTX110546-pro
Package Price Qty
25 μgUSD 299.00
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  • Anti-FADD Protein used in Western Blot (WB). GTX110546-pro
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  • Datasheet
  • Application Information: FADD Protein

Catalog Number GTX110546-pro
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Publication ( 0 )
Product Name FADD Protein
See all FADD products
Full NameFas (TNFRSF6)-associated via death domain
SynonymsMGC8528, MORT1, FADD, mediator of receptor induced toxicity, protein FADD, Fas-associating protein with death domain, growth-inhibiting gene 3 protein, mediator of receptor-induced toxicity, Fas-associating death domain-containing protein, Fas (TNFRSF6)-associated via death domain
BackgroundThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq]
SpeciesHuman
Expression SystemE. coli
ApplicationsWB
Predicted Target Size(KDa)23 Kda(note)
PurificationPurified by conventional chromatography.
Purity90%
Storage Buffer0.1%SDS/PBS
Storage InstructionKeep as concentrated solution. For extended storage add 50% glycerol, aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Apoptosis > Induction > Death domain receptors
  • Cancer > Apoptosis > Induction > Extracellular signals
  • Cell Biology > Apoptosis > Induction from death receptors
  • Cell Biology > Apoptosis > Induction from extracellular signals
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FADD Protein validated data
  • Anti-FADD Protein used in Western Blot (WB). GTX110546-pro
    • GTX110546-pro WB Image
      10ug of GTX110546-pro FADD recombinant protein analyzed using SDS-PAGE and stained with coomassie blue and captured by black and white camera.
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  • Anti-FADD Protein used in Western Blot (WB). GTX110546-pro
    • GTX110546-pro WB Image
      10ug of GTX110546-pro FADD recombinant protein analyzed using SDS-PAGE and stained with coomassie blue and captured by black and white camera.
      Top
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All products are for research use only—Not for use in diagnostic procedures.