FANCC antibody [N1C1]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||63 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , NIH-3T3|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||Fanconi anemia, complementation group C|
|Product Description||Rabbit Polyclonal antibody to FANCC (Fanconi anemia, complementation group C)|
|Background||The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq]|
|Synonyms||FA3 antibody, FAC antibody, FACC antibody, FLJ14675 antibody, FANCC antibody, Fanconi anemia group C protein antibody, "Fanconi anemia, complementation group C antibody"|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FANCC. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|