| Full Name | fibroblast activation protein, alpha |
| Background | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq] |
| Synonyms | DKFZp686G13158 antibody, DPPIV antibody, FAPA antibody, FAP antibody, 170 kDa melanoma membrane-bound gelatinase antibody, integral membrane serine protease antibody, seprase antibody, "fibroblast activation protein, alpha antibody" |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein , Cell projection , lamellipodium membrane; Single-pass type II membrane protein , invadopodium membrane; Single-pass type II membrane protein |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human FAP. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Bovine |
| Predict Reactivity Note | Mouse (89%), Rat (89%), Bovine (93%) |
| Conjugation | Unconjugated |