|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||61 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , A375 , NIH-3T3 , PC-12|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein A.|
|Full Name||Fas-activated serine/threonine kinase|
|Product Description||Rabbit Polyclonal antibody to FAST (Fas-activated serine/threonine kinase)|
|Background||The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq]|
|Synonyms||FAST antibody, FASTK antibody, FAST kinase antibody, fas-activated serine/threonine kinase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human FAST. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Chimpanzee, Bovine|
|Predict Reactivity Note||Dog (95%), Pig (90%), Chimpanzee (99%), Bovine (88%)|