|Full Name||F-box and WD repeat domain containing 8|
|Product Description||Rabbit Polyclonal antibody to FBXW8 (F-box and WD repeat domain containing 8)|
|Background||This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||FBW6 Antibody, F-box and WD repeat domain containing 8 Antibody, FBXW6 Antibody, FBW8 Antibody, FBX29 Antibody, FBXO29 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human FBXW8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (80%), Bovine (80%)|