|Full Name||fibroblast growth factor 12|
|Product Description||Rabbit Polyclonal antibody to FGF12 (fibroblast growth factor 12)|
|Background||The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]|
|Synonyms||FGF12B antibody, FHF1 antibody, FGF12 antibody, fibroblast growth factor 12 antibody, fibroblast growth factor homologous factor 1 antibody, FHF-1 antibody, myocyte-activating factor antibody, fibroblast growth factor 12B antibody, FGF-12 antibody, fibroblast growth factor FGF-12b antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FGF12. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Xenopus laevis, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rat (99%), Xenopus laevis (87%), Chicken (98%), Sheep (100%), Rhesus Monkey (99%), Bovine (100%)|