|Full Name||FGFR1 oncogene partner|
|Product Description||Rabbit Polyclonal antibody to FGFR1OP (FGFR1 oncogene partner)|
|Background||This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq]|
|Synonyms||FOP antibody, FGFR1OP antibody, FGFR1 oncogene partner antibody, fibroblast growth factor receptor 1 oncogene partner antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FGFR1OP. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (81%), Bovine (80%)|