FGR antibody [C3], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||59 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog|
|Product Description||Rabbit polyclonal antibody to FGR (Gardner-Rasheed feline sarcoma viral (v-FGR) oncogene homolog)|
|Background||This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||FLJ43153 antibody, MGC75096 antibody, SRC2 antibody, c-fgr antibody, c-src2 antibody, p55-Fgr antibody, p55c-fgr antibody, p58c-fgr antibody, FGR antibody, c-src-2 proto-oncogene antibody, tyrosine-protein kinase Fgr antibody, proto-oncogene c-Fgr antibody, proto-oncogene tyrosine-protein kinase FGR antibody, c-fgr protooncogene antibody, p55-c-fgr protein antibody, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FGR. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (92%), Rhesus Monkey (92%), Bovine (85%)|