|Full Name||FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)|
|Product Description||Rabbit Polyclonal antibody to FIG4 (FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae))|
|Background||The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq]|
|Synonyms||ALS11 antibody, CMT4J antibody, KIAA0274 antibody, SAC3 antibody, dJ249I4.1 antibody, FIG4 antibody, Sac domain-containing inositol phosphatase 3 antibody, SAC domain-containing protein 3 antibody, "FIG4 homolog, SAC1 domain containing lipid phosphatase antibody", "FIG4 homolog, SAC domain containing lipid phosphatase antibody", "phosphatidylinositol 3,5-bisphosphate 5-phosphatase antibody", polyphosphoinositide phosphatase antibody, "FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae) antibody"|
|Cellular Localization||Endosome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FIG4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (93%), Dog (98%), Pig (97%), Chicken (90%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (96%)|