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1 .GTX55623 FIP1L1 antibody

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FIP1L1 antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsICC/IF, IHC-P, WB
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX55623
Package Price Qty
100 μlUSD 319.00
Add to cart
 
  • Anti-FIP1L1 antibody used in Western Blot (WB). GTX55623
  • Anti-FIP1L1 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX55623
  • Anti-FIP1L1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55623
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  • Datasheet
  • Application Information: FIP1L1 antibody

Catalog Number GTX55623
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Product Name FIP1L1 antibody
See all FIP1L1 products
ApplicationsICC/IF, IHC-P, WB
Application NoteWB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
Form SuppliedLiquid
PurificationAffinity purification

  • Specifications: FIP1L1 antibody

Full Namefactor interacting with PAPOLA and CPSF1
BackgroundThis gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome (HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment with tyrosine kinase inhibitors. Alternative splicing results in multiple
SynonymsRhe Antibody , factor interacting with PAPOLA and CPSF1 Antibody , hFip1 Antibody
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant protein of human FIP1L1
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: FIP1L1 antibody

Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
FIP1L1 antibody validated data
  • Anti-FIP1L1 antibody used in Western Blot (WB). GTX55623
    • GTX55623 WB Image
      Western blot analysis of extracts of various cell lines, using FIP1L1 antibody.
      Top
  • Anti-FIP1L1 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX55623
    • GTX55623 IHC-P Image
      Immunohistochemistry of paraffin-embedded mouse liver using FIP1L1 antibody at dilution of 1:100 (x400 lens).
      Top
  • Anti-FIP1L1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55623
    • GTX55623 ICC/IF Image
      Immunofluorescence analysis of A549 cell using FIP1L1 antibody.
      Top
  • Anti-FIP1L1 antibody used in Western Blot (WB). GTX55623
    • GTX55623 WB Image
      Western blot analysis of extracts of various cell lines, using FIP1L1 antibody.
      Top
  • Anti-FIP1L1 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX55623
    • GTX55623 IHC-P Image
      Immunohistochemistry of paraffin-embedded mouse liver using FIP1L1 antibody at dilution of 1:100 (x400 lens).
      Top
  • Anti-FIP1L1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55623
    • GTX55623 ICC/IF Image
      Immunofluorescence analysis of A549 cell using FIP1L1 antibody.
      Top
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All products are for research use only—Not for use in diagnostic procedures.