FKBP25 antibody [N1C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||25 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||FK506 binding protein 3, 25kDa|
|Product Description||Rabbit Polyclonal antibody to FKBP25 (FK506 binding protein 3, 25kDa)|
|Background||The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq]|
|Synonyms||FKBP-25 antibody, PPIase antibody, FKBP3 antibody, FK506-binding protein 3 (25kD) antibody, 25 kDa FKBP antibody, "FK506-binding protein 25, T-cell antibody", peptidyl-prolyl cis-trans isomerase FKBP3 antibody, 25 kDa FK506-binding protein antibody, rapamycin-selective 25 kDa immunophilin antibody, rotamase antibody, PPIase FKBP3 antibody, immunophilin FKBP25 antibody, rapamycin binding protein antibody, "FK506 binding protein 3, 25kDa antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FKBP25. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Bovine|
|Predict Reactivity Note||Rat (94%), Pig (96%), Bovine (97%)|