FMO1 antibody [N1C2]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||60 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||flavin containing monooxygenase 1|
|Product Description||Rabbit polyclonal antibody to FMO1 (flavin containing monooxygenase 1)|
|Background||Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq]|
|Synonyms||FMO1 antibody, dimethylaniline oxidase 1 antibody, fetal hepatic flavin-containing monooxygenase 1 antibody, dimethylaniline monooxygenase [N-oxide-forming] 1 antibody, FMO 1 antibody, Flavin-containing monooxygenase 1 (fetal liver) antibody, flavin containing monooxygenase 1 antibody|
|Cellular Localization||Microsome membrane , Endoplasmic reticulum membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FMO1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (83%), Rat (82%), Dog (88%), Pig (86%), Rabbit (85%), Rhesus Monkey (98%), Bovine (85%)|