FMO2 antibody [N1C2]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||54 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||flavin containing monooxygenase 2 (non-functional)|
|Product Description||Rabbit polyclonal antibody to FMO2 (flavin containing monooxygenase 2 (non-functional))|
|Background||The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1. [provided by RefSeq]|
|Synonyms||FLJ40826 antibody, FMO1B1 antibody, FMO2 antibody, FMO 2 antibody, dimethylaniline monooxygenase [N-oxide-forming] 2 antibody, "FMO, pulmonary antibody", FMO 1B1 antibody, pulmonary flavin-containing monooxygenase 2 antibody, dimethylaniline oxidase 2 antibody, flavin containing monooxygenase 2 (non-functional) antibody|
|Cellular Localization||Microsome membrane , Endoplasmic reticulum membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FMO2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (83%), Rat (82%), Rabbit (84%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (81%)|