FMO3 antibody [C1C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||60 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||flavin containing monooxygenase 3|
|Product Description||Rabbit Polyclonal antibody to FMO3 (flavin containing monooxygenase 3)|
|Background||The mammalian flavin-containing monooxygenases (FMO; EC 220.127.116.11) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme (Ziegler, 1990 [PubMed 2203193]; Hines et al., 1994 [PubMed 8128486]).[supplied by OMIM]|
|Synonyms||FMOII antibody, MGC34400 antibody, TMAU antibody, dJ127D3.1 antibody, FMO3 antibody, dimethylaniline oxidase 3 antibody, FMO II antibody, FMO 3 antibody, hepatic flavin-containing monooxygenase 3 antibody, dimethylaniline monooxygenase [N-oxide-forming] 3 antibody, FMO form 2 antibody, hepatic flavin-containing monooxygenase-3 antibody, flavin containing monooxygenase 3 antibody|
|Cellular Localization||Microsome membrane , Endoplasmic reticulum membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FMO3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Rabbit, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (81%), Dog (84%), Rabbit (81%), Rhesus Monkey (93%), Chimpanzee (100%), Bovine (83%)|