|Full Name||flavin containing monooxygenase 5|
|Product Description||Rabbit Polyclonal antibody to FMO5 (flavin containing monooxygenase 5)|
|Background||Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq]|
|Synonyms||FMO5 antibody, FMO 5 antibody, dimethylaniline monooxygenase [N-oxide-forming] 5 antibody, hepatic flavin-containing monooxygenase 5 antibody, dimethylaniline oxidase 5 antibody, flavin containing monooxygenase 5 antibody|
|Cellular Localization||Microsome membrane , Endoplasmic reticulum membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FMO5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (87%), Rat (87%), Rabbit (89%), Bovine (93%), Guinea pig (89%)|