|Full Name||fragile X mental retardation 1|
|Product Description||Goat polyclonal antibody to FMRP (aa116-130)|
|Background||Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C). |
|Synonyms||FRAXA, FMR1 (aa116130), MGC87458, fragile X mental retardation 1, FMR1, FMRP, fragile X mental retardation1, POF, POF1|
|Specificity||This antibody is specific for FMRP (aa116-130).|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.