|Full Name||fragile X mental retardation 1|
|Product Description||Rabbit Polyclonal antibody to FMRP (fragile X mental retardation 1)|
|Background||The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). [provided by RefSeq]|
|Synonyms||FMRP antibody, FRAXA antibody, MGC87458 antibody, POF antibody, POF1 antibody, FMR1 antibody, fragile X mental retardation 1 protein antibody, protein FMR-1 antibody, fragile X mental retardation 1 antibody|
|Cellular Localization||Cytoplasm , Nucleus , nucleolus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FMRP. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Zebrafish, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (98%), Zebrafish (82%), Xenopus laevis (91%), Bovine (96%)|