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FOXA2 antibody

Anti-FOXA2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX100309

Cat. No. GTX100309

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-Fr

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all FOXA2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-Fr 1:100-1:1000
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Predict Reactivity

Rat, Zebrafish, Chicken, Japanese Medaka, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FOXA2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1240824

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

forkhead box A2 , HNF3B , TCF3B

Cellular Localization

Nucleus

Background

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-FOXA2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX100309

GTX100309 IHC-Fr Image

FOXA2 antibody detects FOXA2 protein by immunohistochemical analysis.
Sample: Frozen sectioned mouse E10.5 embryonic neuron tube.
Green: FOXA2 protein stained by FOXA2 antibody (GTX100309) diluted at 1:250.
Blue: Fluoroshield with DAPI (GTX30920).

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

Application Reference

Y Zhang et al. Stem Cell Res 2023; : 103201 Human induced pluripotent stem cell line from fibroblasts (HEBHMUi015-A) and chondrogenic differentiation
Application : ICC/IF
Mingjing Zhang et al. Stem Cell Research 2023; Human Induced pluripotent stem cell (iPSC) line (HEBHMUi014-A) derived from a patient with Alzheimer's disease
Application : ICC/IF
Reactivity : Human
Shih SC et al. Am J Transl Res 2017; 9 (3) : 1114-1126 Pigment epithelium-derived factor (PEDF) peptide promotes the expansion of hepatic stem/progenitor cells via ERK and STAT3-dependent signaling.
Liu H et al. PLoS One 2017; 12 (6) : e0179353 testosterone improves the differentiation efficiency of *-producing cells from human induced pluripotent stem cells.
Application : ICC/IF
Reactivity : Human
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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169