| Full Name | forkhead box O1 |
| Product Description | Rabbit polyclonal antibody to FOXO1 |
| Background | FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14 |
| Synonyms | FKH1, FKHR, FOXO1A, FOXO1, forkhead, Drosophila, homolog of, in rhabdomyosarcoma, forkhead box protein O1, forkhead box protein O1A, forkhead box O1 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | FOXO1 |
| Immunogen | Peptide sequence around aa.254~258 (A-A-S-M-D) derived from Human FKHR/FOXO1A. |
| Antigen Species | Human |
| Species Reactivity | Human |