FPGT antibody [N2C2], Internal
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||67 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , Raji |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||fucose-1-phosphate guanylyltransferase|
|Product Description||Rabbit polyclonal antibody to FPGT (fucose-1-phosphate guanylyltransferase)|
|Background||L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. [provided by RefSeq]|
|Synonyms||GFPP antibody, FPGT antibody, fucose-1-phosphate guanyltransferase antibody, GDP-beta-L-fucose pyrophosphorylase antibody, fucose-1-phosphate guanylyltransferase antibody, GDP-L-fucose diphosphorylase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FPGT. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (83%), Pig (85%), Rabbit (82%), Rhesus Monkey (96%), Bovine (83%)|