FRAT1 antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||29 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||frequently rearranged in advanced T-cell lymphomas|
|Product Description||Rabbit Polyclonal antibody to FRAT1 (frequently rearranged in advanced T-cell lymphomas)|
|Background||The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq]|
|Synonyms||FLJ97193 antibody, FRAT1 antibody, proto-oncogene FRAT1 antibody, frequently rearranged in advanced T-cell lymphomas 1 antibody, FRAT-1 antibody, frequently rearranged in advanced T-cell lymphomas antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FRAT1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|