|Full Name||fused in sarcoma|
|Product Description||Rabbit polyclonal antibody to FUS (FUSion (involved in t(12;16) in malignant liposarcoma))|
|Background||This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq]|
|Synonyms||ALS6 antibody, FUS1 antibody, HNRNPP2 antibody, POMP75 antibody, TLS antibody, FUS antibody, fus-like protein antibody, oncogene FUS antibody, fusion gene in myxoid liposarcoma antibody, 75 kDa DNA-pairing protein antibody, RNA-binding protein FUS antibody, heterogeneous nuclear ribonucleoprotein P2 antibody, oncogene TLS antibody, translocated in liposarcoma protein antibody, fused in sarcoma antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FUS. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (98%), Pig (99%), Chimpanzee (100%), Bovine (100%)|