|Full Name||coagulation factor IX|
|Product Description||Rabbit Polyclonal antibody to Factor IX (coagulation factor IX)|
|Background||This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq]|
|Synonyms||FIX antibody, HEMB antibody, MGC129641 antibody, MGC129642 antibody, PTC antibody, F9 antibody, factor 9 antibody, plasma thromboplastin component antibody, plasma thromboplastic component antibody, coagulation factor IX antibody, Christmas factor antibody, serine protease antibody, FIX F9 antibody, F9 p22 antibody, factor IX F9 antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Factor IX. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Dog, Cat, Pig, Rabbit, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (80%), Dog (87%), Cat (83%), Pig (87%), Rabbit (82%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (82%)|