Fatty Acid Synthase antibody [N1N2], N-term
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||273 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , Molt-4 , Mouse liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||fatty acid synthase|
|Product Description||Rabbit Polyclonal antibody to Fatty Acid Synthase (fatty acid synthase)|
|Background||The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq]|
|Synonyms||FAS antibody, MGC14367 antibody, MGC15706 antibody, OA-519 antibody, SDR27X1 antibody, FASN antibody, "short chain dehydrogenase/reductase family 27X, member 1 antibody", fatty acid synthase antibody|
|Cellular Localization||Cytoplasm , Melanosome |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Fatty Acid Synthase. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Bovine|
|Predict Reactivity Note||Rat (85%), Pig (80%), Bovine (81%)|