|Product Description||Rabbit polyclonal antibody to Ferrochelatase (ferrochelatase (protoporphyria))|
|Background||The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||EPP antibody, FCE antibody, FECH antibody, heme synthase antibody, "ferrochelatase, mitochondrial antibody", protoheme ferro-lyase antibody, protoporphyria antibody, heme synthetase antibody, ferrochelatase antibody|
|Cellular Localization||Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Ferrochelatase. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (94%), Rat (94%), Zebrafish (80%), Xenopus laevis (87%), Pig (89%), Chicken (82%), Chimpanzee (100%), Bovine (92%)|