|Full Name||fibrillin 1|
|Product Description||Rabbit Polyclonal antibody to Fibrillin 1 (fibrillin 1)|
|Background||This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq]|
|Synonyms||FBN antibody, MASS antibody, MFS1 antibody, OCTD antibody, SGS antibody, SSKS antibody, WMS antibody, FBN1 antibody, fibrillin 15 antibody, fibrillin-1 antibody, fibrillin 1 antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Fibrillin 1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (90%), Dog (92%), Pig (95%), Bovine (95%)|