|Full Name||fibrinogen beta chain|
|Product Description||Rabbit Polyclonal antibody to Fibrinogen beta (fibrinogen beta chain)|
|Background||The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq]|
|Synonyms||MGC104327 antibody, MGC120405 antibody, FGB antibody, fibrinogen beta chain antibody, "fibrinogen, B beta polypeptide antibody"|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Fibrinogen beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Xenopus laevis (81%), Pig (88%), Chicken (82%), Bovine (87%)|