Fibrinogen gamma antibody
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||52 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , human plasma , HepG2 sup. , Mouse plasma|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||fibrinogen gamma chain|
|Product Description||Rabbit polyclonal antibody to Fibrinogen gamma (fibrinogen gamma chain)|
|Background||The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||FGG antibody, "fibrinogen, gamma polypeptide antibody", fibrinogen gamma chain antibody|
|Cellular Localization||Secreted |
|Target||Fibrinogen gamma |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Fibrinogen gamma. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (91%), Pig (88%), Chicken (81%), Bovine (88%)|