|Full Name||filamin B, beta|
|Product Description||Mouse Monoclonal antibody [GT1372] to Filamin B (filamin B, beta)|
|Background||This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]|
|Synonyms||TAP Antibody , filamin B, beta Antibody , FLN1L Antibody , FLNB Antibody , ABP-278 Antibody , FH1 Antibody , LRS1 Antibody , ABP-280 Antibody , FLN-B Antibody , SCT Antibody , TABP Antibody , AOI Antibody|
|Cellular Localization||Isoform 1: Cytoplasm , cell cortex , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 6: Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (97%), Bovine (99%)|