Filamin B antibody [N1], N-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||278 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , U87-MG , NIH-3T3|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein A.|
|Full Name||filamin B, beta|
|Product Description||Rabbit Polyclonal antibody to Filamin B (filamin B, beta)|
|Background||This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]|
|Synonyms||ABP-278 antibody, ABP-280 antibody, AOI antibody, DKFZp686A1668 antibody, DKFZp686O033 antibody, FH1 antibody, FLN1L antibody, LRS1 antibody, SCT antibody, TABP antibody, TAP antibody, FLNB antibody, thyroid autoantigen antibody, ABP-280 homolog antibody, filamin-3 antibody, filamin homolog 1 antibody, actin-binding-like protein antibody, Larsen syndrome 1 (autosomal dominant) antibody, actin binding protein 278 antibody, filamin-B antibody, beta-filamin antibody, filamin B, beta antibody|
|Cellular Localization||Isoform 1: Cytoplasm , cell cortex , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 6: Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chicken, Bovine|
|Predict Reactivity Note||Rat (98%), Chicken (97%), Bovine (99%)|