|Full Name||folate receptor 2 (fetal)|
|Product Description||Rabbit Polyclonal antibody to Folate receptor beta (folate receptor 2 (fetal))|
|Background||The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||FR-P3 Antibody, folate receptor 2 (fetal) Antibody, FBP/PL-1 Antibody, FOLR2 Antibody, FBP Antibody, FR-BETA Antibody, BETA-HFR Antibody|
|Cellular Localization||Cell membrane; Lipid-anchor , GPI-anchor , Secreted |
|Target||Folate receptor beta|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Folate receptor beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (84%), Rhesus Monkey (97%), Bovine (86%)|