|Full Name||folylpolyglutamate synthase|
|Product Description||Rabbit polyclonal antibody to Folylpolyglutamate synthase (folylpolyglutamate synthase)|
|Background||This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq]|
|Synonyms||FPGS antibody, tetrahydrofolylpolyglutamate synthase antibody, tetrahydrofolate synthase antibody, folylpoly-gamma-glutamate synthetase antibody, "folylpolyglutamate synthase, mitochondrial antibody", folylpolyglutamate synthase antibody|
|Cellular Localization||Mitochondrion , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Folylpolyglutamate synthase. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (81%)|