|Full Name||frizzled homolog 8 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Frizzled 8 (frizzled homolog 8 (Drosophila))|
|Background||This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq]|
|Synonyms||FZ-8 antibody, hFZ8 antibody, FZD8 antibody, frizzled homolog 8 antibody, "frizzled 8, seven transmembrane spanning receptor antibody", frizzled-8 antibody, frizzled homolog 8 (Drosophila) antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Frizzled 8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (100%), Rat (100%)|