|Full Name||GRB2-associated binding protein 2|
|Product Description||Rabbit Polyclonal antibody to GAB2 (GRB2-associated binding protein 2)|
|Background||This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq]|
|Synonyms||KIAA0571 antibody, GAB2 antibody, Grb2-associated binder 2 antibody, pp100 antibody, GRB2-associated-binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GRB2-associated binding protein 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GAB2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (91%), Rat (90%)|