|Full Name||gamma-aminobutyric acid (GABA) A receptor, alpha 1|
|Product Description||Rabbit polyclonal antibody to GABA A Receptor alpha 1 (gamma-aminobutyric acid (GABA) A receptor, alpha 1)|
|Background||This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]|
|Synonyms||ECA4 antibody, EJM antibody, EJM5 antibody, GABRA1 antibody, GABA(A) receptor subunit alpha-1 antibody, gamma-aminobutyric acid receptor subunit alpha-1 antibody, "gamma-aminobutyric acid (GABA) A receptor, alpha 1 antibody"|
|Cellular Localization||Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein , Cell membrane; Multi-pass membrane protein |
|Target||GABA A Receptor alpha 1|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Zebrafish, Rabbit, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Zebrafish (89%), Rabbit (100%), Chicken (97%), Rhesus Monkey (100%), Bovine (100%)|