|Full Name||gamma-aminobutyric acid (GABA) A receptor, alpha 2|
|Product Description||Rabbit polyclonal antibody to GABA A Receptor alpha 2 (gamma-aminobutyric acid (GABA) A receptor, alpha 2)|
|Background||GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||FLJ97076 antibody, GABRA2 antibody, GABA(A) receptor subunit alpha-2 antibody, gamma-aminobutyric acid receptor subunit alpha-2 antibody, "gamma-aminobutyric acid (GABA) A receptor, alpha 2 antibody"|
|Cellular Localization||Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein , Cell membrane; Multi-pass membrane protein |
|Target||GABA A Receptor alpha 2|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (99%), Xenopus laevis (92%), Rhesus Monkey (100%), Bovine (99%)|