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  • GABA A Receptor alpha 4 antibody, Internal

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1 .GTX31003 GABA A Receptor alpha 4 antibody, Internal

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GABA A Receptor alpha 4 antibody, Internal


  • Host / ClonalityGoat Polyclonal
  • ApplicationsIHC-P, WB
  • Species reactivityHuman
Cat No: GTX31003
Package Price Qty
100 μgUSD 319.00
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  • Anti-GABA A Receptor alpha 4 antibody, Internal used in IHC (Formalin-fixed paraffin-embedded sections). GTX31003
  • Anti-GABA A Receptor alpha 4 antibody, Internal used in Western Blot (WB). GTX31003
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  • Datasheet

  • Application Information: GABA A Receptor alpha 4 antibody, Internal

Catalog Number GTX31003
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Product Name GABA A Receptor alpha 4 antibody, Internal
See all GABA A Receptor alpha 4 products
ApplicationsIHC-P, WB
Application NoteApprox. 70kDa band observed in Human Brain (Cerebellum and Frontal Cortex) lysates (calculated MW of 61.6kDa according to NP_000800.2). Recommended concentration: 0.1-0.3µg/ml. In paraffin embedded Human Cortex shows patchy staining near or at the neuronal cell membrane.. Recommended concentration, 2-4µg/ml.
Positive ControlsThe peptide used to generate this antibody is available for purchase (GTX31003-PEP).
Form SuppliedLiquid
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by ammonium sulphate precipitation followed by antigen affinity chromatography

  • Specifications: GABA A Receptor alpha 4 antibody, Internal

Full Namegamma-aminobutyric acid type A receptor alpha4 subunit
BackgroundGamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
SynonymsGABRA4 Antibody
HostGoat
ClonalityPolyclonal
IsotypeIgG
ImmunogenPeptide with sequence C-EKAKRKTSKPPQE, from the internal region of the protein sequence according to NP_000800.2.
Antigen SpeciesHuman
Species ReactivityHuman
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
 		Bovine
ConjugationUnconjugated

  • Storage Conditions: GABA A Receptor alpha 4 antibody, Internal

Storage BufferTris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Storage InstructionKeep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
GABA A Receptor alpha 4 antibody, Internal validated data
  • Anti-GABA A Receptor alpha 4 antibody, Internal used in IHC (Formalin-fixed paraffin-embedded sections). GTX31003
    • GTX31003 IHC-P Image
      GTX31003 (2.5µg/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
      Top
  • Anti-GABA A Receptor alpha 4 antibody, Internal used in Western Blot (WB). GTX31003
    • GTX31003 WB Image
      GTX31003 (0.1µg/ml) staining of Human Frontal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
      Top
  • Anti-GABA A Receptor alpha 4 antibody, Internal used in IHC (Formalin-fixed paraffin-embedded sections). GTX31003
    • GTX31003 IHC-P Image
      GTX31003 (2.5µg/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
      Top
  • Anti-GABA A Receptor alpha 4 antibody, Internal used in Western Blot (WB). GTX31003
    • GTX31003 WB Image
      GTX31003 (0.1µg/ml) staining of Human Frontal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
      Top
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